What is boc anhydride?

Boc anhydride stands for t-butoxycarbonyl anhydride, and is a reagent commonly used in organic synthesis for the protection of amines. It is also known as Boc-Oxalyl chloride or Boc anhydride.

Boc anhydride is a colorless to pale yellow liquid that is sensitive to moisture and should be stored in a tightly sealed container in a cool, dry place. It should be handled with care as it is a strong irritant to the skin, eyes, and respiratory system.

In organic synthesis, Boc anhydride reacts with amines to form Boc-protected amines, which are commonly used in peptide synthesis and other applications. The Boc protecting group can be removed under mild acidic conditions, making it a versatile and widely used protecting group in organic chemistry.

Overall, Boc anhydride is an important reagent in organic synthesis for the protection of amines and other functional groups, and its use has been widely documented in the literature.